TAG HIV Basic Science, Vaccines, and Cure Project Blog
By Richard Jefferys, Project Director at Treatment Action Group (TAG).
recent posts
- In The News: CAR-T Cells for HIV
- TAG’s HIV Cure-Related Clinical Research Listing: Background on the March 2026 Update
- TAG’s HIV Cure-Related Clinical Research Listing: Background on the February 2026 Update
- TAG’s HIV Cure-Related Clinical Research Listing: Background on the December 2025 and January 2026 Updates
- TAG’s HIV Cure-Related Clinical Research Listing: Background on the November 2025 Update
Category: Post-treatment controllers
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For August 2025, there were eight updates to the TAG listing. New Additions A study sponsored by the ANRS RHIVIERA project in France plans to investigate the JAK1/JAK2 Inhibitor baricitinib and the mTOR Inhibitor sirolimus in people who started antiretroviral therapy (ART) soon after HIV acquisition. Baricitinib is also being tested in several other ongoing…
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The were ten updates to the TAG listing in July 2025. New Additions Four newly registered HIV cure-related studies were added: Oxford University in the UK is sponsoring AbVax, a phase II combination trial that will administer therapeutic vaccines designed to induce T cell responses against HIV plus two broadly neutralizing antibodies (bNAbs), teropavimab…
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For March, April, and May 2025, there were 38 updates to entries in TAG’s listing. The majority involved the addition of links to results presented at the annual Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco. As is covered further below, this period has seen a horrific and unprecedented political attack on scientific…
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The April 2024 update to TAG’s listing features eight changes. New Additions Three new studies were added this month. All are protocols being initiated by the U.S. government-funded ACTG Network (formerly known as the AIDS Clinical Trials Group, recently revised to Advancing Clinical Therapeutics Globally). The Antiretrovirals Combined With Antibodies for HIV-1 Cure In Africa…
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The March 2024 revision to TAG’s listing includes 26 updates. The annual Conference on Retroviruses and Opportunistic Infections (CROI) took place in Denver from March 3-6, and the addition of links to results from HIV cure-related studies presented at the meeting typically makes this the busiest month for changes — hence the delay to this…
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No new HIV cure-related trials or studies have been added to the clinicaltrials.gov registry over the past month. Two trials in the listing have changed status: A study sponsored by the ANRS in France investigating the link between specific immune system genetics (MHC B35/53Bw4TTC2) and post-treatment control of HIV is now open for enrollment. Participants…
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The first press conference of the upcoming IAS 2023 meeting was held yesterday evening (US time) and featured several cure-related presentations. Most notably, Asier Sáez-Cirión and Alexandra Calmy described a possible case of an HIV cure (or at least extended remission) in an individual in Geneva who received a stem cell transplant to treat cancer.…
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The 24th International AIDS Conference (AIDS 2022) officially opens on Friday in Montreal, but a Zoom press conference today shared news of results from several studies, including two case reports relevant to HIV cure research. Jana Dickter from the City of Hope hospital in Los Angeles described another instance of “prolonged HIV-1 remission” after receipt…
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This year’s virtual Conference on Retroviruses and Opportunistic Infections (CROI) ended on February 24th. Abstracts from the meeting are now available publicly in an abstract book and searchable database. Webcasts of all the presentations are due to become available around March 25th. Several presenters reported potentially encouraging developments in HIV cure research, in addition to…
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The Conference on Retroviruses and Opportunistic Infections (CROI) is taking place virtually again this year, running from February 12th to February 24th. In a session today on HIV cure research, Yvonne Bryson and colleagues from the IMPAACT research network presented important news about another potential example of an HIV cure achieved by stem cell transplantation.…