TAG HIV Basic Science, Vaccines, and Cure Project Blog
By Richard Jefferys, Project Director at Treatment Action Group (TAG).
recent posts
- In The News: CAR-T Cells for HIV
- TAG’s HIV Cure-Related Clinical Research Listing: Background on the March 2026 Update
- TAG’s HIV Cure-Related Clinical Research Listing: Background on the February 2026 Update
- TAG’s HIV Cure-Related Clinical Research Listing: Background on the December 2025 and January 2026 Updates
- TAG’s HIV Cure-Related Clinical Research Listing: Background on the November 2025 Update
Category: Gene therapy
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The were ten updates to the TAG listing in July 2025. New Additions Four newly registered HIV cure-related studies were added: Oxford University in the UK is sponsoring AbVax, a phase II combination trial that will administer therapeutic vaccines designed to induce T cell responses against HIV plus two broadly neutralizing antibodies (bNAbs), teropavimab…
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For March, April, and May 2025, there were 38 updates to entries in TAG’s listing. The majority involved the addition of links to results presented at the annual Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco. As is covered further below, this period has seen a horrific and unprecedented political attack on scientific…
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Last month’s revision to TAG’s listing included ten updates. New Additions There was only one new HIV cure-related trial identified in registries. The protocol, named Tatelo Plus, represents a follow up to a prior smaller evaluation of dual broadly neutralizing antibodies (bNAbs) in children with HIV in Botswana (the Tatelo study). The research project is…
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There are seven updates in the July 2024 revision to TAG’s listing. New Additions Only one new cure-related clinical trial was identified in registries over the past month, which is a revised version of a protocol that was previously withdrawn. The study is sponsored by the US Military HIV Research Program (MHRP), and will assess…
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The 25th International AIDS Conference is taking place in Munich, Germany from July 22-26, with several pre-conference events scheduled on Sunday, July 21st. Remote access will also be possible for registered attendees, with recordings made publicly available at some point after the meeting ends. Links to events and sessions related to HIV cure research are…
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There are 14 updates in the June 2024 revision to TAG’s listing. New Additions Three newly registered studies have been added: two interventional and one observational. The German company Hookipa Biotech is sponsoring a clinical trial assessing two therapeutic HIV vaccine candidates based on an arenavirus vector platform in people with HIV on antiretroviral…
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There are ten updates in the May 2024 revision to TAG’s listing. No new HIV cure-related clinical trials or observational studies were identified in registries this month, and one protocol was withdrawn: a combination study codenamed RV582 sponsored by the US Military HIV Research Program (MHRP). No explanation for the withdrawal is provided in the…
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A total of nine changes were made to TAG’s listing for the February 2024 update. New Additions Two new clinical trials have been added, both not yet open for enrollment. Researchers at the City of Hope Medical Center in Los Angeles are planning to initiate a trial of a novel approach to chimeric antigen receptor…
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A total of eight changes were made to TAG’s listing for the first monthly update of 2024. New Additions One new study has been added from the Pan African Clinical Trials Registry: Scientists affiliated with the Centre for the AIDS Programme of Research in South Africa (CAPRISA) are launching a phase I cure-related trial investigating…
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No new HIV cure-related trials or studies were added to the clinicaltrials.gov registry over the past month. A total of eight updates have been made to TAG’s listing: A phase II study sponsored by AbbVie that was added to the listing in September (see prior blog update) is now open for enrollment. The company initiated…